kn 62 (Selleck Chemicals)

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Selleck Chemicals kn 62
Kn 62, supplied by Selleck Chemicals, used in various techniques. Bioz Stars score: 93/100, based on 28 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/kn+62/KN-62/pmc12663277-57-20-21
Average 93 stars, based on 28 article reviews

kn 62 - by Bioz Stars, 2026-10

93/100 stars

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Article Title: An unconventional autophagic pathway that inhibits ATP secretion during apoptotic cell death
Article Snippet: Chemicals: zVAD.fmk (Becton Dickinson, 550377), DAPI (Sigma, 10236276001), ARL67156 (Sigma, A265), etoposide (Sigma, E1383), E64D (EST, Calbiochem, 330005), pepstatin (Sigma, P4265), polybrene (Sigma, H9268), bafilomycin A1 (Sigma, B1793), rapamycin (Selleckchem, S1039), staurosporine (Sigma, S4400), mitoxantrone (MTX, Sigma, M6545), quinacrine (Sigma, Q3251), KN-62 and JNJ-47965567 (Tocris, 1277 and 5299, respectively), dimethyl fumarate (DMF, Sigma, 242926), clodronate (CLD, Sigma, 233183), 4,4’-Diisothiocyanostilbene-2,2’-disulfonic acid, disodium salt (DIDS, MedChemExpress, HY-D0086).

Article Title: Derivation and Characterization of Murine and Amphibian Müller Glia Cell Lines
Article Snippet: Adenosine triphosphate (ATP) disodium (50 μM; Selleck Chemicals, Houston, TX, Cat# S1985), KN-62 (1 μM; Selleck Chemicals, Cat# S7422), 2′-3′-O-(4-benzoylbenzoyl) adenosine 5′-triphosphate (50 μM; BzATP) triethylammonium salt (Tocris, Minneapolis, MN, Cat# 3312), and glutamate (100–1000 μM) were used.

Article Title: Non-catalytic allostery in α-TAT1 by a phospho-switch drives dynamic microtubule acetylation.
Article Snippet: The rest of the kinase inhibitors were purchased as indicated: Staurosporine (catalog # 569397; Sigma-Aldrich), LJI308 (catalog # SML1788; Sigma-Aldrich), Y-27632 (catalog # Y-5301; LC Laboratories), Gö 6976 (catalog # 365250; Sigma-Aldrich), Gö 6983 (catalog # G1918; Sigma-Aldrich), H-89 (catalog # B1427; Sigma-Aldrich), D4476 (catalog # 1770; BioVision), KN-62 (catalog # S7422; Selleck Chemicals), KU-57788 (catalog # HY-11006; MedChemExpress), Purvalanol B (catalog # SYN-1070; AdipoGen Life Sciences), KT-5823 (catalog # 10010965; Cayman Chemicals), PD0332991 (catalog # PZ0199; Sigma-Aldrich), BMS265246 (catalog # S2014; Selleck Chemicals), AT7519 (catalog # S1524; Selleck Chemicals), TTP22 (catalog # S6536; Selleck Chemicals), and Ellagic acid (catalog # S5516; Selleck Chemicals).

In Vitro:

Article Title: Calcium channel blockers potentiate gemcitabine chemotherapy in pancreatic cancer
Article Snippet: .. For in vitro experiments, Gemcitabine, Amlodipine, Nifedipine, BAPTA-AM, KN-62, Paclitaxel, 5-Flurouracil, SN-38, and Oxaliplatin were purchased from Selleck Chem (Houston, TX), W-7 from Sigma Aldrich/Millipore (Burlington, MA), reconstituted in DMSO per the manufacturer instructions, and used as described. .. The NFAT-inhibitor peptide was purchased from Cayman Chemical (Ann Arbor, MI), reconstituted in PBS, and also used as described.

Incubation:

Article Title: Development of intestinal tissue-resident T cells in early-life mice before and after weaning
Article Snippet: .. Intestines were incubated in RPMI 1640 medium supplemented with 10% FBS (complete medium), 1 mM Dithiothreitol (Sigma-Aldrich), and 10 μM KN-62 (Selleckchem), and stirred gently for 45 min at 37 °C. .. The supernatant containing IELs was isolated on a 40%/75% Percoll gradient (GE Healthcare).

Saline:

Article Title: Social memory maintenance relies on social interaction-induced proteolytic products of neuroligin 1.
Article Snippet: The secondary antibodies include: goat anti-rabbit (1:2000; Cat# SA00001-2, Proteintech), goat anti-mouse (1:2000; Cat# SA00001-1, Proteintech), Cy3–conjugated Goat Anti-Rabbit IgG(H + L) (1:1000, Cat# SA00009-2, Proteintech), and Alexa Fluor 488 Goat Anti–rabbit IgG (1:200; Cat# A-11008, Thermo Fisher). .. The reagents include MRK-560 (Cat# HY-14174, MCE), KN-62 (Cat# A8180, APEXbio), GI254023X (Cat# S8660, Selleck), Anisomycin (Cat# B6674, APExBIO), NBQX (Cat# N171, Sigma-Aldrich), Picrotoxin (PTX, Cat# R284556, Sigma-Aldrich), AP5 (Cat# 0106, Tocris), 1.25% Tribromoethanol (Cat# M2920, EasyCheck), DMEM (Cat# D6429, Sigma-Aldrich), FBS (Cat# 12003 C, Sigma-Aldrich), Lipofectamine 3000 (Cat# L3000150, Thermo Fisher), Paraformaldehyde (Cat# A500684, Sangon Biotech), Clozapine N-oxide (Cat# HY-17366, MedChemExpress), Saline (Cat# CZ0034, Leagene), PBS (Cat# 311- 010-CL, Wisent), Streptavidin-conjugated FITC (Cat# SA1001, Thermo Fisher), Mounting medium (Cat# P0131-25ml, Beyotime), Mineral oil (Cat# BS927, Biosharp) and TAT-PBD/REV/S3 peptides (Genscript). ..

Article Title: Social memory maintenance relies on social interaction-induced proteolytic products of neuroligin 1
Article Snippet: The secondary antibodies include: goat anti-rabbit (1:2000; Cat# SA00001-2, Proteintech), goat anti-mouse (1:2000; Cat# SA00001-1, Proteintech), Cy3–conjugated Goat Anti-Rabbit IgG(H + L) (1:1000, Cat# SA00009-2, Proteintech), and Alexa Fluor 488 Goat Anti–rabbit IgG (1:200; Cat# A-11008, Thermo Fisher). .. The reagents include MRK-560 (Cat# HY-14174, MCE), KN-62 (Cat# A8180, APEXbio), GI254023X (Cat# S8660, Selleck), Anisomycin (Cat# B6674, APExBIO), NBQX (Cat# N171, Sigma-Aldrich), Picrotoxin (PTX, Cat# R284556, Sigma-Aldrich), AP5 (Cat# 0106, Tocris), 1.25% Tribromoethanol (Cat# M2920, EasyCheck), DMEM (Cat# D6429, Sigma-Aldrich), FBS (Cat# 12003 C, Sigma-Aldrich), Lipofectamine 3000 (Cat# L3000150, Thermo Fisher), Paraformaldehyde (Cat# A500684, Sangon Biotech), Clozapine N-oxide (Cat# HY-17366, MedChemExpress), Saline (Cat# CZ0034, Leagene), PBS (Cat# 311-010-CL, Wisent), Streptavidin-conjugated FITC (Cat# SA1001, Thermo Fisher), Mounting medium (Cat# P0131-25ml, Beyotime), Mineral oil (Cat# BS927, Biosharp) and TAT-PBD/REV/S3 peptides (Genscript). ..

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